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KMID : 1035220140060010001
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Korean Journal of Neuromuscular Disorders
2014 Volume.6 No. 1 p.1 ~ p.6
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Anatomy and Physiology of Neuromuscular Junction
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Kwon O-Hyun
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Abstract
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Neuromuscular junction (NMJ) has a sophisticated structure to transfer neural signal securely to muscle fiber. Synaptogenesis of NMJ is developmentally well preserved along invertebrate and vertebrate, and the morphology of NMJ itself corresponds with its physiological role. In this review, Subcellular specialization of the NMJ, pre- and post?synaptic compartment and synaptic cleft, and their physiology will be described briefly.
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KEYWORD
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Acetylcholine, Motor endplate, Neuromuscular junction, Nicotinic acetylcholine receptor
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